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MAX, Recombinant, Human (Myc-associated Factor X, bHLHd4, Class D Basic Helix-loop-helix Protein 4, MGC10775, MGC11225, MGC18164, MGC34679, MGC36767, orf1, Protein Max)

Cat no: M2450-01H

MAX, Recombinant, Human (Myc-associated Factor X, bHLHd4, Class D Basic Helix-loop-helix Protein 4, MGC10775, MGC11225, MGC18164, MGC34679, MGC36767, orf1, Protein Max)

MAX is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. In contrast to Myc, which is highly regulated during progression through the cell cycle, Max is highly stable and is much more abundant than Myc. Recombinant human MAX protein, fused to His-tag at C-terminus, was expressed in E. coli.\n\nSource: \nRecombinant corresponding to aa1-160 of human MAX 6x His tagged expressed in E. coli.\n\nAA Sequence:\nMSDNDDIEVE SDEEQPRFQS AADKRAHHNA LERKRRDHIK DSFHSLRDSV PSLQGEKASR AQILDKATEY IQYMRRKNHT HQQDIDDLKR QNALLEQQVR ALEKARSSAQ LQTNYPSSDN SLYTNAKGST ISAFDGGSDS SSESEPEEPQ SRKKLRMEAS LEHHHHHH\n\nApplications: \nSuitable for use in Western Blot. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

M2450-01H

Size

100ug

Applications

WB

Form

Supplied as a liquid in 20mM Tris HCl, pH 8.0, 1mM DTT, 10% glycerol.

Purity

~ 90% (SDS-PAGE). Purified by using conventional chromatography techniques.

References

1. Burbano HA., et al. (2010) Science. 328(5979):723-5.

Alternative Names

MYC Associated Factor X, bHLHd5, bHLHd6, bHLHd7, bHLHd8

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