MaxiK(beta)2 (I186) pAb

Cat no: BS9144

Supplier: Bioworld Technology, Inc.

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Additional Information

MaxiK(beta) subunit 1 consists of two putative transmembrane domains, an extracellular loop containing three consensus sequences for N-linked glycosylation and four cysteine residues that might form disulfide bridges. MaxiK(beta) subunit 1, one of four subunits in the MaxiK(beta) family, is expressed predominately in smooth muscle tissue but is also found in brain, liver and lymphatic tissues. MaxiK(beta) subunit 1 associates with MaxiK(alpha) to form a calcium-activated potassium channel (also designated MaxiK and BK channel). MaxiK(beta) subunit 1 increases the sensitivity of the MaxiK(alpha) to calcium and voltage. The MaxiK(alpha)/(beta)1 channel is the most sensitive of all Maxi channels to calcium. MaxiK(beta) plays an important role in vasoregulation by controlling the sensitivity of MaxiK channels to calcium, which leads to the proper amount of arterial relaxation.

Catalogue number:	BS9144
Reactivities:	Human, Mouse, Rat
Hosts:	Rabbit
Applications:	Immunohistochemistry, Western Blot
Size:	100ug/100ul
Swiss prot:	Q16558
Dilutions:	WB: 1:500~1:1000 IHC: 1:50~1:200
Form:	liquid
Storage buffer:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration:	1ug/ul
Antigen:	Synthetic peptide, corresponding to amino acids 154-203 of Human MaxiK(beta)2.
Species:	MaxiK(beta)2 (I186) pAb detects endogenous levels of MaxiK(beta)2 protein.
Molecular weight:	~ 27 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp:	Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names:	KCNMB 1; KCNMB1; Hbeta1; hslo beta; K(VCA)beta 1; K(VCA)beta; BKbeta; BKbeta1;
Additional info:	For research use only, not for use in diagnostic procedure.

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MaxiK(beta)2 (I186) pAb

Cat no: BS9144

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