Home  >  Products  >  MBL-C (Mannose-binding Lectin C, MBP-C, Collectin-1, MBP1, Mannan-binding Protein, RA-reactive Factor P28A Subunit, RARF/P28A, MBL2, COLEC1)
MBL-C (Mannose-binding Lectin C, MBP-C, Collectin-1, MBP1, Mannan-binding Protein, RA-reactive Factor P28A Subunit, RARF/P28A, MBL2, COLEC1)

MBL-C (Mannose-binding Lectin C, MBP-C, Collectin-1, MBP1, Mannan-binding Protein, RA-reactive Factor P28A Subunit, RARF/P28A, MBL2, COLEC1)

Cat no: M2250-01J

Supplier: United States Biological
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Mannose Binding Lectin (MBL) also called mannose- or mannan-binding protein (MBP) is a member of the group of collectins. MBL is an oligomeric lectin that recognizes carbohydrates as mannose and N- acetylglucosamine on pathogens. MBL contains a cysteine rich, a collagen like and a carbohydrate recognition domain. It forms a complex with C1r/C1s like serine proteases designated MASPs that proteolytically cleave C4, C2 and C3. MBL is able to activate the complement pathway independent of the classical and alternative complement activation pathways. The MBL-MASP pathway (better known as the lectin pathway) is antibody and C1q
Catalogue number: M2250-01J
Reactivities: Mouse
Hosts: Rat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide.
P type: Mab
Isotype: IgG2a
Purity: Purified by Protein G affinity chromatography.
References: 1. Liu, H et al; Characterization and Quantification of Mouse Mannan-Binding Lectins (MBL-A and MBL- C) and Study of Acute Phase Responses. Scand J Immunol 2001, 53: 489. 2. Sastry, K et al; Molecular characterization of the mouse mannose-binding proteins. The mannose- binding protein A but not C is an acute phase reactant. J Immunol 1991, 147: 692.
Additional info: Recognizes mouse MBL-C.

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