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MC 1568

Cat no: 015833


Supplier: United States Biological
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A selective class II (IIa) histone deacetylase (HDAC II) inhibitor. It exhibits tissue-selective inhibition between members of class II acetylases in vivo, particularly in skeletal muscle and the heart. It arrests myogenesis through the stabilization of myocyte enhancer factor 2D (MEF2D)-HDAC3/4 complex.
Catalogue number: 015833
Size: 10mg
Alternative names: 3-[4-(3-(3-Fluorophenyl)-3-oxo-1-propen-1-yl)-1-methyl-1H-pyrrol-2-yl]-N-hydroxy-2-propenamide;
References: Mai, A. et al.: Mol.Pharmacol., 72, 1111 (2007); Mai, A. et al.: J.Med.Chem., 48, 3344 (2005); Nebbioso, A. et al.: Eur. Mol. Biol. Org. Rep., 10, 776 (2009);

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