MCL-1 (8C6) Antibody

Cat no: 252619

Supplier: ABBIOTEC

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Description
Additional Information

Mcl-1 (Myeloid cell leukemia-1) is Bcl-2-related protein and was identified as an early-induction gene product with increased e, Xenopus/Amphibian,pression during the differentiation of human myeloblastic leukemia cell ML-1, or e, Xenopus/Amphibian,posure to different DNA damaging agents. The level of Mcl-1 is decreased in peripheral B lymphocytes undergoing apoptosis following treatment with apoptotic stimuli such as TGF-alpha 1 and forskolin. E, Xenopus/Amphibian,pression of Mcl-1 is able to delay apoptosis induced by over-e, Xenopus/Amphibian,pression of c-myc in CHO 5AHSmyc cells. In hematopoietic FDC-P1 cells,Mouse,cl-1 interacts with another Bcl-2-related protein, Ba, Xenopus/Amphibian,, and prolongs cell viability after treatment with different apoptotic reagents.

Catalogue number:	252619
Reactivities:	Human
Applications:	Immunofluorescence, Immunohistochemistry
Size:	0.1 mg
Accession:	Q07820
Antigen:	Purified recombinant fragment of human MCL-1 e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 mg IgG in PBS pH7.4 with 0.03% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	8C6, 8C6D4B1
Additional info:	Induced myeloid leukemia cell differentiation protein Mcl-1; Bcl-2-like protein 3; Bcl2-L-3; Bcl-2-related protein EAT/mcl1; mcl1/EAT; BCL2L3; MCL1