MCT4 (F265) Peptide

Cat no: BS3331P

Supplier: Bioworld Technology, Inc.

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Monocarboxylates, such as lactate and pyruvate, play an integral role in cellular metabolism. Lactic acid is produced in large quantities as a result of glycolysis, which provides the majority of ATP to cells under normal physiological conditions. However, accumulation of lactic acid leads to a decrease in intracellular pH and cessation of glycolysis. In order for glycolysis to continue at a high rate, lactic acid must be transported out of the cell. This transport process is carried out by a family of monocarboxylate transporters (MCTs),which function as proton symports and are stereoselective for L-lactate.The MCT family consists of at least eight members, MCT1-8, which contain between 10-12 transmembrane-helical (TM) domains, with the amino and carboxy termini located in the cytoplasm. MCT1 is widely expressed and is the major form of MCTs in tumor cells and erythrocytes. MCT2 is highly expressed in liver and testis, while MCT3 and MCT4 are predominantly expressed in skeletal muscle.

Catalogue number:	BS3331P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	O15427
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide MCT4 (F265). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	SLC16A4; MCT4; MCT5; Monocarboxylate transporter 4
Additional info:	This peptide can be used with studies using BS3331 MCT4 (F265) pAb.

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MCT4 (F265) Peptide

Cat no: BS3331P

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