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MDH1 pAb

Cat no: BS60457

MDH1 pAb

Cytosolic malate dehydrogenase (MDHC or cMDH) is an important NAD-dependent enzyme involved in glycometabolism that catalyzes the formation of oxaloacetate and NADH from L-malate and NAD. MDHC is highly expressed in brain, heart and skeletal muscle and plays a role in aerobic energy production for muscle contraction, transmission of neuronal signals, absorption/ resorption pathways, collagen-supporting functions, dead cell phagocytosis, as well as pathways involved in gas exchange and cell division. Furthermore, MDHC is a regulatory subunit of the nucleic acid-conducting channel (NACh). MDHC functions as a homodimer and is highly conserved in plants, animals and bacteria. The activity of MDHC is controlled by the sesquiterpenoid juvenile hormone (JH) and the steroid hormone ecdysone.

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SPECIFICATIONS

Catalog Number

BS60457

Size

100ug/100ul

Applications

WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

A synthetic peptide corresponding to residues in Human MDH1.

Species

MDH1 pAb detects endogenous levels of MDH1 protein.

Dilutions

WB: 1:500~1:1000\r

Swiss Prot

P40925

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul

Storage Buffer

1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Additional Info

For research use only, not for use in diagnostic procedure.

Molecular Weight

~ 36 kDa

Alternative Names

Malate dehydrogenase, cytoplasmic; Cytosolic malate dehydrogenase; Diiodophenylpyruvate reductase; MDHA; MDHC; cMDH

SUPPLIER INFO

Bioworld Technology, Inc.

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