MEK1/2 (Ser218/222) Antibody

Cat no: 252554

Supplier: ABBIOTEC

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Description
Additional Information

Dual specificity mitogen-activated protein kinase kinase 1 (MEK1/2) catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. MEK1/2 activates ERK1 and ERK2 MAP kinases. Defects in MEK1/2 are a cause of cardiofaciocutaneous syndrome (CFC syndrome), also known as cardio-facio-cutaneous syndrome. CFC syndrome is characterized by distinctive facial appearance, heart defects and mental retardation.

Catalogue number:	252554
Reactivities:	Human, Bovine, Chicken/Bird, Rabbit, Xenopus/Amphibian, Zebrafish/Fish
Applications:	Western Blot
Size:	0.1 ml
Accession:	Q02750
Antigen:	KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser218/222 of human MEK1/2.
Format:	Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.
P type:	Rabbit Polyclonal Antibody,Porcinehosphospecific Antibody
Isotype:	Rabbit IgG
Additional info:	MEK1/2; Dual specificity mitogen-activated protein kinase kinase 1; MAP kinase kinase 1; MAPKK 1; MKK1; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1; MAP2K1; MEK1; PRKMK1