MEK1 (MAPKK1) Antibody

Cat no: 252148

Supplier: ABBIOTEC

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Description
Additional Information

MEK1 (MAPKK1) catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. MEKI (MAPKK1) activates ERK1 and ERK2 MAP kinases, enzymes which are involved in numerous signal transduction pathways. Defects in MEK1 (MAPKK1) are a cause of cardiofaciocutaneous syndrome (CFC syndrome), also known as cardio-facio-cutaneous syndrome. CFC syndrome is characterized by a distinctive facial appearance, heart defects and mental retardation.

Catalogue number:	252148
Reactivities:	Human
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	Q02750
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within human MEK1 (MAPKK1) .
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.5 % BSA with 0.09% sodium azide. Antibody was purified by immunogen-affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	MAPKK1; Dual specificity mitogen-activated protein kinase kinase 1; MAP kinase kinase 1; MAPKK1; ERK activator kinase 1; MAPK/ERK kinase 1; MEK1; MAP2K1; PRKMK1