mGluR2/3 Antibody

Cat no: 253171

Supplier: ABBIOTEC

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Description
Additional Information

The metabotropic glutamate receptors (mGluRs) are key receptors in the modulation of e, Xenopus/Amphibian,citatory synaptic transmission in the central nervous system. They are implicated in many forms of neural plasticity as well as learning and memory and drug abuse. Group I metabotropic glutamate receptors (consisting of mGluR1 and mGluR5) are G-protein-coupled neurotransmitter receptors that are localized in the perisynaptic region of the postsynaptic membrane. When activated, Group I mGluRs lead to stimulation of phospholipase and activation of Protein Kinase C. In contrast, activation of Group II metabotropic receptors (mGluR2 and mGluR3) leads to inhibition of adenylate cyclase. The mGluR2 subunit has been shown to be required for long-term potentiation at the mossy fiber input in the hippocampus.

Catalogue number:	253171
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 ml
Accession:	P31421
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of rat mGluR2/3.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by immunogen affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Metabotropic glutamate receptor 2; mGluR2; Grm2; Gprc1b; Mglur2