mGluR5/1 Antibody

Cat no: 253172

Supplier: ABBIOTEC

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Description
Additional Information

The metabotropic glutamate receptors (mGluRs) are key receptors in the modulation of e, Xenopus/Amphibian,citatory synaptic transmission in the central nervous system. They are implicated in many forms of neural plasticity as well as learning and memory and drug abuse. Group I metabotropic glutamate receptors (consisting of mGluR1 and mGluR5) are G-protein-coupled neurotransmitter receptors that are localized in the perisynaptic region of the postsynaptic membrane. When activated, Group I mGluRs lead to stimulation of phospholipase and activation of Protein Kinase C. The mGluR5 receptor appears to be essential for late phase LTP in area CA1 of the hippocampus.

Catalogue number:	253172
Reactivities:	Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 ml
Accession:	P31424
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of rat mGluR5/1.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by immunogen affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Metabotropic glutamate receptor 5; mGluR5; m5; Gprc1e; Mglur5