MGP, Recombinant, Human, aa20-96, His-tag (Matrix Gla Protein, Cell Growth-inhibiting Gene 36 Protein, MGLAP, GIG36)

Cat no: M2419-91

Supplier: United States Biological

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MGP, is a protein involved in regulating calcification in the extracellular matrix, in particular in cartilage and arteries. MGP is a vitamin K-dependent protein, and contains five to six residues of Gla, a Ca2+ binding amino acid requiring vitamin K-dependent gamma carboxylase for its formation. It is found in human bone extracts, likely formed by COOH-terminal processing by carboxypeptidase B-like enzymatic activity. Source: Recombinant corresponding to aa20-96 from human MGP, fused to His-tag at N-terminal expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MYESHESMES YELNPFINRR NANTFISPQQ RWRAKVQERI RERSKPVHEL NREACDDYRL CERYAMVYGY NAAYNRYF Molecular Weight: ~11.8kD Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Catalogue number:	M2419-91
Size:	100ug
Form:	Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 10% glycerol.
Purity:	~90% (SDS-PAGE)
References:	1. Cancela L.et al. (1990) J Biol Chem. 265:15040-15048. 2. Hale J.E.et al. (1991) J. Biol. Chem. 266:21145-21149.

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MGP, Recombinant, Human, aa20-96, His-tag (Matrix Gla Protein, Cell Growth-inhibiting Gene 36 Protein, MGLAP, GIG36)

Cat no: M2419-91

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