Milbemycins are a complex family of macrocyclic lactones containing a highly characteristic spiroketal group produced by Streptomyces hydroscopicus subsp. aureolarcrimosus. Milbemycin A4 is the dominant member of a group of analogues containing a 25-ethyl substituent. Milbemycin A4 is a highly selective and potent nematocide and insecticide. Like the closely related avermectins, milbemycins are thought to act on chloride-gated ion channels.
Purity: >95% by HPLC
Solubility: Soluble in ethanol, methanol, DMF or DMSO.
Related to: Avermectin B1a, Avermectin B1b, Milbemycin A3, Milbemycin D, Nemadectin