Cell-permeable. A potent, cAMP-specific phosphodiesterase (PDEIII ) inhibitor (IC?? = 0.45 and 1.0um for PDEIIIA and PDEIIIB, respectively). It inhibits other PDE isoforms at much higher concentrations. Milrinone has positive inotropic (stimulates cardiac muscle contractions) and vasodilatory effects when administered in vivo.
Solubility:
~10mg/ml (DMSO)
Molecular Weight:
~211.22
Storage and Stability:
Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Products ![Milrinone (1, 6- dihydro- 2- methyl- 6- oxo- [3, 4'- bipyridine]- 5- carbonitrile, WIN 47, 203)](/system/suppliers/default_product_images/000/000/160/main/US-Biological-Life-Sciences.jpg?1386100414)
