ML-IAP (E211) Peptide

Cat no: BS3534P

Supplier: Bioworld Technology, Inc.

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Inhibitor of apoptosis proteins (IAPs) contain conserved, unique aminoterminal baculovirus IAP repeats (BIRs) and usually a C-terminal RING finger domain. Immunoprecipitation and Western blot analysis indicate that ML-IAP, also known as melanoma inhibitor of apoptosis protein, kidney inhibitor of apoptosis protein (KIAP), livin or BIRC7, binds to caspase-3, -7, and -9, but only inhibits caspase-9. Additionally, ML-IAP physically interacts with SMAC through its BIR domain with a very high affinity and this interaction is very specific. The gene which encodes ML-IAP maps to human chromosome 20q13.3. There is controversy regarding the localization of this protein and its involvement in apoptosis, but it has been suggested that ML-IAP may play a complex role in the regulation of apoptosis.

Catalogue number:	BS3534P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	Q96CA5
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide ML-IAP (E211). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Baculoviral IAP repeat-containing protein 7; EC=6.3.2.-; Kidney inhibitor of apoptosis protein; KIAP; Livin; Melanoma inhibitor of apoptosis protein; ML-IAP; RING finger protein 50; UNQ5800/PRO19607/PRO21344; KIAP; LIVIN; MLIAP; RNF50; BIRC7
Additional info:	This peptide can be used with studies using BS3534 ML-IAP (E211) pAb.

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ML-IAP (E211) Peptide

Cat no: BS3534P

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