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Monosodium urate (MSU (ready-to-use), Uric acid (ready-to-use))

Monosodium urate (MSU (ready-to-use), Uric acid (ready-to-use))

Cat no: 045039

Supplier: United States Biological
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NLRP3/NALP3 inflammasome activator. Specially crystallized and tested for biological activity. Stimulates the caspase-1 activating NLRP3/NALP3 inflammasome, resulting in the production of active IL-1beta and IL-18. Storage and Stability: Short-term Storage: +4 degrees C Long-term Storage: -20 degrees C Stable for at least 1 year after receipt when stored at -20 degrees C.
Catalogue number: 045039
Size: 10mg
Form: In PBS.
Alternative names: MSU (ready-to-use), Uric acid (ready-to-use)
References: Product Reference: ?Monosodium urate crystals in inflammation and immunity: Y. Shi, et al.; Immunol. Rev. 233, 203 (2010) ?Crystals of monosodium urate monohydrate enhance lipopolysaccharide-induced release of interleukin 1 beta by mononuclear cells through a caspase 1-mediated process: E.J. Giamarellos-Bourboulis, et al.; Ann. Rheum. Dis. 68, 273 (2009) ?Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases: M.T. Shio, et al.; PLoS Pathog. 5, e1000559 (2009) ?Gout-associated uric acid crystals activate the NALP3 inflammasome: F. Martinon, et al.; Nature 440, 237 (2006) ?

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