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Mouse Alpha-tocopherol transfer protein (TTPA) ELISA Kit

Cat no: KTE70048

Mouse Alpha-tocopherol transfer protein (TTPA) ELISA Kit

TTPa encodes a soluble protein that binds alpha-trocopherol, a form of vitamin E, with high selectivity and affinity. This protein plays an important role in regulating vitamin E levels in the body by transporting vitamin E between membrane vesicles and facilitating the secretion of vitamin E from hepatocytes to circulating lipoproteins. Mutations in this gene cause hereditary vitamin E deficiency (ataxia with vitamin E deficiency, AVED) and retinitis pigmentosa.\nUsing rat alpha-Ttp to screen a liver cDNA library, followed by PCR, Arita et al. (1995) cloned full-length human alpha-TTP. The deduced 278-amino acid protein has a calculated molecular mass of 31.7 kD and shares 94% identity with rat alpha-Ttp. Northern blot analysis of several human tissues detected a 4.5-kb alpha-TTP transcript in liver only.

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SPECIFICATIONS

Catalog Number

KTE70048

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

50500

Accession

Q8BWP5

Additional Info

Mouse Alpha-tocopherol transfer protein (TTPA) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse TTPA. No significant cross-reactivity or interference between Mouse TTPA and analogues was observed.

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