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Mouse Anti-Human ABCB11 monoclonal antibody, clone G-7

Mouse Anti-Human ABCB11 monoclonal antibody, clone G-7

Cat no: CABT-L1025

Supplier: Creative Diagnostics
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Mouse Human Anti-ABCB11 monoclonal antibody for WB, IP, IF, IHC-P, ELISA. ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of proteins that catalyze the transport of molecules across extra- and intracellular membranes through the energy of ATP hydrolysis. ABC genes comprise seven subfamilies, designated ABC1, Mdr/TAP, MRP, ALD, OABP, GCN20 and White. The secretion of bile salt molecules from blood into bile is a major driving force for bile formation. Bile salt export pump (BSEP) is a member of the Mdr/TAP subfamily of ABC transporters that mediates the transport of bile acids across the hepatocyte canalicular membrane and regulates bile acid-dependent bile secretion. BSEP contains putative phosphorylation sites for protein kinase A, protein kinase C (PKC) and Ca2+-calmodulin dependent kinase II, whose regulation may be dependent on bile salt concentration.
Catalogue number: CABT-L1025
Reactivities: Human, Mouse, Rat
Hosts: Mouse
Applications: ELISA
Conjugates: Unconjugated
Clone: G-7
Gene: 839353
Target: ABCB11
Isotype: IgG2a
Clonality: Monoclonal
Storage temp: Store at 4° C. DO NOT FREEZE! Stable for one year from the date of shipment. Non-hazardous.

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