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Mouse Anti-Human CD45 monoclonal antibody, clone IJ41 [Alexa Fluor® 594]

Mouse Anti-Human CD45 monoclonal antibody, clone IJ41 [Alexa Fluor® 594]

Cat no: DMAB-SYL01

Supplier: Creative Diagnostics
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Mouse Anti-Human CD45 monoclonal antibody for IHC-P. CD45 is a 180-240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes and platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.
Catalogue number: DMAB-SYL01
Reactivities: Human
Hosts: Mouse
Clone: IJ41
Gene: 5788
Target: PTPRC
Isotype: IgG1
Clonality: Monoclonal
Storage temp: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

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