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Mouse Anti-Human Copeptin(C-term) monoclonal antibody, clone 5917

Cat no: CABT-L1119

Mouse Anti-Human Copeptin(C-term) monoclonal antibody, clone 5917

Mouse Anti-Human Copeptin monoclonal antibody for ELISA. Copeptin is a 39 amino acid glycosylated peptide that is a proteolytic product derived from a precursor which also contains Vasopressin and Neurophysin 2 peptides. The precursor protein is synthesized and cleaved in the hypothalamus before transport to the pituitary for storage and release. Copeptin is secreted in equimolar amounts with Vasopressin. It is more stable than Vasopressin and serves as a surrogate indicator of Vasopressin release. Vasopressin plays a major role in blood pressure regulation through control of water retention in the kidney and vascular tone. Serum levels of Copeptin are associated with metabolic syndrome, insulin resistance, sepsis, and heart dysfunction following myocardial infarction. Human Copeptin shares 79% sequence identity with mouse and rat Copeptin.

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SPECIFICATIONS

Catalog Number

CABT-L1119

Applications

ELISA

Hosts

Mouse

Reactivities

Hum

Conjugates

Unconj

Clone

5917

Target

CT-proAVP

Isotype

IgG1

Clonality

Monoclonal

Storage Temp

Unspecified, storage at 2–8 °C. For long term storage, store at -20°C to -70°C.

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