Mouse anti Human RBP4 monoclonal antibody, clone 404117

Cat no: CABT-L231

Supplier: Creative Diagnostics

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Mouse Anti-Human RBP4 monoclonal antibody for ELISA(Cap). Retinol (also known as vitamin A) is unstable and insoluble in the aqueous solution. However, retinol becomes quite stable and soluble in plasma due to its tight interaction with retinol-binding protein 4 (RBP4), also known as plasma retinol-binding protein. A prototypic member of the lipocalin superfamily, RBP4 has a beta-barrel structure with a well-defined cavity. It is secreted from the liver, a process requiring the availability of retinol. RBP4 delivers retinol from the liver to the peripheral tissues. In plasma, the RBP4-retinol complex interacts with transthyretin (TTR), also known as thyroxine-binding protein and prealbumin. The retinol-RBP4-TTR complex prevents the loss of RBP4 by filtration through the kidney and increases the stability of the retinol-RBP4 complex. Defects in RBP4 cause retinol-binding protein deficiency, which affects night vision. Human and mouse RBP4 share 86% amino acid sequence identity.

Catalogue number:	CABT-L231
Reactivities:	Human
Hosts:	Mouse
Conjugates:	Unconjugated
Clone:	404117
Gene:	5950
Target:	RBP4
Isotype:	IgG1
Clonality:	Monoclonal
Storage temp:	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

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Mouse anti Human RBP4 monoclonal antibody, clone 404117

Cat no: CABT-L231

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