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Mouse anti Human TIMP1 monoclonal antibody, clone 74626

Mouse anti Human TIMP1 monoclonal antibody, clone 74626

Cat no: CABT-L234

Supplier: Creative Diagnostics
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Mouse Anti-Human TIMP1 monoclonal antibody for ELISA(Cap), FC, IHC, WB. Tissue inhibitors of metalloproteinases or TIMPs are a family of proteins that regulate the activation and proteolytic activity of the zinc enzymes known as matrix metalloproteinases (MMPs). There are four members of the family, TIMP-1, TIMP-2, TIMP-3, and TIMP-4. TIMP-1 is a glycoprotein with a molecular mass of 28 kDa produced by a wide range of cell types. TIMP-1 inhibits active MMP-mediated proteolysis by forming an N-terminal, non-covalent binary complex with the MMP active site. TIMP-1 also associates C-terminally with Pro-MMP-9 in a complex which may play a role in regulating activation. Independent of MMPs, TIMP-1 has been shown to have a role in tissue homeostasis.
Catalogue number: CABT-L234
Reactivities: Human
Hosts: Mouse
Conjugates: Unconjugated
Clone: 74626
Gene: 7076
Target: TIMP1
Isotype: IgG2B
Clonality: Monoclonal
Storage temp: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

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