Mouse Epithelial neutrophil activating peptide 78 (ENA-78) ELISA Kit

ENA-78 is a CXC chemokine that was originally isolated from media conditioned by the growth of a mouse lung type-II alveolar epithelial cell line (A549) stimulated by IL-1 or TNF. The full-length cDNA encodes a 114 amino acid (aa) residue precursor protein with a 36 aa residue signal peptide that is cleaved to generate the 78 aa residue secreted protein. ENA-78 shares significant amino acid sequence identity with NAP-2 (53%), GRO,, and (52%, 48% and 51%, respectively), and IL-8 (22%). The gene for ENA-78 has been mapped to chromosome 4q13-q21. Like other CXC chemokines, ENA-78 is a neutrophil attractant and activator in vitro. Based on cross-desensitization experiments, it has been suggested that ENA-78 activity can be mediated through the IL-8 receptor system.

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SPECIFICATIONS

Catalog Number

KTE71561

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

20311

Accession

P50228

Additional Info

Mouse Epithelial neutrophil activating peptide 78 (ENA-78) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse CXCL5. No significant cross-reactivity or interference between Mouse CXCL5 and analogues was observed.