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Mouse Lamina-associated polypeptide 2, isoform alpha (TMPO) ELISA Kit

Cat no: KTE70153

Mouse Lamina-associated polypeptide 2, isoform alpha (TMPO) ELISA Kit

Thymopoietin is a protein involved in the induction of CD90 in the thymus. The thymopoetin (TMPO) gene encodes three alternatively spliced mRNAs encoding proteins of 75 kDa (alpha), 51 kDa (beta) and 39 kDa (gamma) which are ubiquitously expressed in all cells. The human TMPO gene maps to chromosome band 12q22 and consists of eight exons. TMPO alpha is present diffusely expressed with the cell nucleus while TMPO beta and gamma are localized to the nuclear membrane. TMPO beta is a human homolog of the murine protein LAP2 (lamina-associated polypeptide 2). LAP2 plays a role in the regulation of nuclear architecture by binding lamin B1 and chromosomes. This interaction is regulated by phosphorylation during mitosis.

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SPECIFICATIONS

Catalog Number

KTE70153

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

21917

Accession

Q61033

Additional Info

Mouse Lamina-associated polypeptide 2, isoform alpha (TMPO) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse TMPO. No significant cross-reactivity or interference between Mouse TMPO and analogues was observed.

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