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Mouse Tankyrase-2 (TNKS2) ELISA Kit

Mouse Tankyrase-2 (TNKS2) ELISA Kit

Cat no: KTE70105

Supplier: Abbkine Scientific Co.Ltd.
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The poly(ADP-ribose) polymerase (PARP) tankyrase-1 contains an ankyrin-repeat domain that binds to various partners, including the telomeric protein TRF1 (telomere-repeat-binding factor 1) and the vesicular protein IRAP (insulin-responsive aminopeptidase). TRF1 binding recruits tankyrase-1 to telomeres and allows its PARP activity to regulate telomere homoeostasis. By contrast, IRAP binding and the Golgi co-localization of tankyrase-1 with IRAP might allow tankyrase-1 to affect the targeting ofIRAP-containing vesicles. A closely related protein, tankyrase-2, has also been implicated in vesicular targeting. Unlike tankyrase-1, tankyrase-2 has not been shown to have PARP activity. In addition, it has not been implicated in telomere homoeostasis, because it did not interact with TRF1 in previous studies.
Catalogue number: KTE70105
Reactivities: Mouse
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q3UES3
Gene: 74493
Additional info: Mouse Tankyrase-2 (TNKS2) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse TNKS2. No significant cross-reactivity or interference between Mouse TNKS2 and analogues was observed.

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