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Mouse Thioredoxin-interacting protein (TXNIP) ELISA Kit

Cat no: KTE70043


Supplier: Abbkine Scientific Co.Ltd.
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Exposure to vitamin D3 (1,25-dihydroxyvitamin D3) or phorbol ester induces the bipotent HL-60 cell promyelocytic leukemia cell line to differentiate into monocytes/macrophages, whereas retinoic acid and dimethylsulfoxide induce differentiation towards granulocytes. The differentiation is accompanied by regulation of MYC , FOS , FMS (CSF1R), and myeloblastin (PRTN3;). By differential screening of HL60 cell lines, Chen and DeLuca (1994) identified a cDNA encoding TXNIP, which they termed VDUP1. The deduced TXNIP protein has 391 amino acids. Ribonuclease protection analysis showed dramatically increased expression of TXNIP in response to vitamin D3 but not to phorbol ester. Chen and DeLuca (1994) concluded that TXNIP is not involved in the differentiation process.
Catalogue number: KTE70043
Reactivities: Mouse
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q8BG60
Gene: 56338
Additional info: Mouse Thioredoxin-interacting protein (TXNIP) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse TXNIP. No significant cross-reactivity or interference between Mouse TXNIP and analogues was observed.

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