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Mouse TOM1-like protein 1 (TOM1L1) ELISA Kit

Cat no: KTE70078

Mouse TOM1-like protein 1 (TOM1L1) ELISA Kit

Mice hypomorphic for Tom1l2 exhibited numerous infections and tumors compared to wild-type littermates. Associated with this increased risk for infection and tumor formation, apparently healthy Tom1l2 hypomorphs also had splenomegaly, elevated B- and T-cell counts, and an impaired humoral response, although at a reduced penetrance.\nFurthermore, cellular localization studies showed that a Tom1l2-GFP fusion protein colocalizes with Golgi compartments, supporting the role of Tom1l2 in cellular trafficking, while molecular modeling and bioinformatic analysis of Tom1l2 illustrated a structural basis for a functional role in trafficking. These results indicate a role for Tom1l2 in the immune response and possibly in tumor suppression.

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SPECIFICATIONS

Catalog Number

KTE70078

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

71943

Accession

Q923U0

Additional Info

Mouse TOM1-like protein 1 (TOM1L1) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse TOM1L1. No significant cross-reactivity or interference between Mouse TOM1L1 and analogues was observed.

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