Mouse Treg Flow(TM) Kit (FOXP3 Alexa Fluor(R) 488/CD4 APC/CD25 PE)

Cat no: 320018

Supplier: BioLegend

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Description
Additional Information

T regulatory (Treg) cells are a subset of T lymphocytes which is characterized by CD4+/CD25+/FOXP3+. These naturally occurring Treg cells originate in the thymus, and comprise 2-10% of peripheral CD4+ T cells. It has been shown that Treg cells are able to inhibit T cells proliferation and cytokine production and play critical roles in preventing autoimmunity as well as in controlling tumor immunity and transplantation tolerance. Impaired Treg function or Treg cell deficiency will develop variety of autoimmune diseases, while higher frequency of Treg cells will cause hypo-immune response to pathogens. BioLegend's Mouse Treg Flow(TM) Kit is designed and formulated specifically for immunofluroscence staining and flow cytometric analysis of mouse Treg cells in a mixed lymphocyte population. This kit is composed of flurochrome conjugated anti-mouse CD4, CD25 and FOXP3 antibodies and the critical buffers. It is easy to use for identification of Treg cells.

Catalogue number:	320018
Reactivities:	Mouse
Hosts:	Mouse
Applications:	Flow Cytometry, Immunocytochemistry
Size:	25 tests
Clone:	150D
Gene:	20371,317382,50943
Storage buffer:	This kit is guaranteed for three months. Upon receipt, store at 4C, and protected from prolonged exposure to light. Do not freeze.
Isotype:	Mouse IgG1, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	Forkhead box protein P3, Scurfin, JM2, IPEX, Zinc finger protein JM2