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Mouse Trinucleotide repeat-containing gene 6B protein (TNRC6B) ELISA Kit

Cat no: KTE70087

Mouse Trinucleotide repeat-containing gene 6B protein (TNRC6B) ELISA Kit

The deduced 1,203-amino acid protein contains an RNA recognition motif. RT-PCR ELISA detected moderate expression in all tissues and specific brain regions examined, with highest expression in cerebellum.\nSchneider et al. (2006) stated that the 1,727-amino acid TNRC6B protein contains a glycine/tryptophan (GW)-rich N-terminal domain, a central glutamine-rich region, and a C-terminal RNA recognition motif.\nTNRC6B copurified with a cytoplasmic HeLa cell protein complex containing AGO2 (EIF2C2), DICER, and MOV10. Epitope-tagged TNRC6B coimmunoprecipitated with tagged AGO1 (EIF2C1) and tagged AGO2. TNRC6B was required to mediate microRNA-guided mRNA cleavage in HeLa cell culture.

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SPECIFICATIONS

Catalog Number

KTE70087

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

213988

Accession

Q8BKI2

Additional Info

Mouse Trinucleotide repeat-containing gene 6B protein (TNRC6B) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse TNRC6B. No significant cross-reactivity or interference between Mouse TNRC6B and analogues was observed.

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SUPPLIER INFO

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