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Mouse Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) ELISA Kit

Cat no: KTE70131

Mouse Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) ELISA Kit

TRAIL is a member of the tumor necrosis factor (TNF) family of cytokines and induces apoptosis in a wide variety of cells. Using a combination of PCR and library screening, the authors isolated cDNAs corresponding to the TRAILR2 coding region. The predicted 440-amino acid protein contains a putative signal peptide, 2 cysteine-rich pseudorepeats characteristic of TNF receptor (TNFR) family members, a transmembrane domain, and an intracellular death domain. The death domain of TRAILR2 shares 30% identity with that of TNFR1. Overall, the TRAIL receptors TRAILR2 and TRAILR1 (DR4) are 58% identical. Northern blot analysis indicated that TRAILR2 was expressed as a 4.4-kb mRNA in all tissues tested, with the highest levels of expression in peripheral blood lymphocytes, spleen, and ovary.

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SPECIFICATIONS

Catalog Number

KTE70131

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

21933

Accession

Q9QZM4

Additional Info

Mouse Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse TNFRSF10B. No significant cross-reactivity or interference between Mouse TNFRSF10B and analogues was observed.

SUPPLIER INFO

Abbkine Scientific Co.Ltd.

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