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Mouse X-box-binding protein 1 (XBP1) ELISA Kit

Mouse X-box-binding protein 1 (XBP1) ELISA Kit

Cat no: KTE70004

Supplier: Abbkine Scientific Co.Ltd.
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X-box binding protein 1is a a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1). The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1(S), which is the functionally active transcription factor.
Catalogue number: KTE70004
Reactivities: Mouse
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: O35426
Gene: 22433
Additional info: Mouse X-box-binding protein 1 (XBP1) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse XBP1. No significant cross-reactivity or interference between Mouse XBP1 and analogues was observed.

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