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MRCKbeta (F1665) Peptide

Cat no: BS2382P

MRCKbeta (F1665) Peptide

Protein kinases comprise a large group of encoded factors that regulate cellular processes by catalyzing the transfer of a phosphate group to a hydroxyl acceptor in serine, threonine or tyrosine residues. Myotonic dystrophy kinaserelated Cdc42-binding (DMPK-like) kinases-alpha and beta (MRCK-alpha, beta) contain a cysteine-rich motif and a putative pleckstrin homology domain. MRCKs can phosphorylate nonmuscle Myosin light chain and influences Actin-Myosin contractility. MRCK-alpha can phosphorylate and activate LIM kinases downstream of Cdc42, which leads to inactivation of ADF/Cofilin and to Actin cytoskeletal reorganization. MRCK-alpha can also influence neurite outgrowth promoted by Cdc42 and Rac.

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SPECIFICATIONS

Catalog Number

BS2382P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide MRCKbeta (F1665). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

Q9Y5S2

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS2382 MRCKbeta (F1665) pAb.

Alternative Names

MRCKbeta; CDC42BPB; KIAA1124; MRCK beta

SUPPLIER INFO

Bioworld Technology, Inc.

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