MRP2 Antibody

Cat no: 251463

Supplier: ABBIOTEC

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Description
Additional Information

MRP2 (Canalicular multispecific organic anion transporter 1) mediates hepatobiliary e, Xenopus/Amphibian,cretion of numerous organic anions. MRP2 is found on the apical membrane of polarized cells in the liver, kidney, intestine, with the highest e, Xenopus/Amphibian,pression in liver. Defects in MRP2 are the cause of Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia, an increase in the urinary e, Xenopus/Amphibian,cretion of coproporphyrin isomer I, deposition of melanin-like pigment in hepatocytes, and prolonged retention of sulfobromophthalein, but otherwise normal liver function.

Catalogue number:	251463
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	Q92887
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human MRP2.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	MRP2; Multidrug resistance-associated protein 2; Canalicular multispecific organic anion transporter 1; ATP-binding cassette sub-family C member 2; Canalicular multidrug resistance protein; ABCC2; CMOAT; CMOAT1; CMRP