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MSGA (Melanoma growth stimulatory activity, growth-regulated alpha protein, GRO-alpha(1-73), C-X-X motif chemokine 1, neutrophil-activating protein 3, NAP-3, CXCL1)

MSGA (Melanoma growth stimulatory activity, growth-regulated alpha protein, GRO-alpha(1-73), C-X-X motif chemokine 1, neutrophil-activating protein 3, NAP-3, CXCL1)

Cat no: C8298-01A

Supplier: United States Biological
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MSGA belongs to the intercrine alpha (chemokine CXC) familly. In this family, the first two of the four conserved residues are separated by a single amino acid. MSGA has chemotactic activity for neutrophils and may play a role in inflammation. MSA is secreted and subsequently proteolytically processed at the N-terminus by peripheral blood monocytes to form GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73). In vitro, these processed forms show a 30 fold increase in chemotactic activity. The unprocessed precursor has a length of 107 amino acids and a predicted molecular weight of 11.3KD. Applications: Suitable for use in ELISA, and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile 40-50% glycerol, ddH2O. Reconstituted product is stable for 12 months at -20 degrees C. Aliquot and store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: C8298-01A
Reactivities: Human
Hosts: Mouse
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a lyophilized powder in PBS, pH 7.2. Reconstitute with 100ul sterile ddH2O.
P type: Mab
Isotype: IgG
Purity: Purified by affinity chromatography.
Additional info: Recognizes human MSGA.

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