A potent mTOR (mammalian target of rapamycin) inhibitor (IC?? =~10nM for mTORC1 and mTORC2, respectively). Displays no activity against PI 3-kinase or 76 other kinases tested.
Solubility:
DMSO
Molecular Weight:
~465.54
Storage and Stability:
Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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