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mu-Conotoxin SIIIA

Cat no: STC-450

mu-Conotoxin SIIIA

mu-Conotoxin SIIIA. A Blocker of TTX-Sensitive Nav1.2, Nav1.3 and Nav1.4 Voltage-Gated Na+ Channels.

mu-Conotoxin SIIIA is a synthetic peptide purified to homogeneity, originally isolated from the Conus striatus venom. mu-Conotoxin SIIIA reversibly blocks TTX-sensitive voltage-gated Na+ channels in small-diameter DRG neurons.
It also irreversibly blocks NaV1.2, NaV1.3 and NaV1.4 channels expressed in Xenopus oocytes in a dose- and time-dependent manner. No inhibition is detected on Nav1.5, Nav1.7 or Nav1.8 channels.

Ion Channel Modulators; Voltage - Gated Na+ Channel Blockers

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SPECIFICATIONS

Catalog Number

STC-450

Size

50 micro g

Purity

>98%

Concentration

0.5 - 3 uM

Shipping Temp

Room Temperature

Molecular Weight

2207 Da

SUPPLIER INFO

Alomone Labs Ltd.

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