MX2 Peptide

Members of the Dynamin family include GTPase, microtubule-associated proteins that are involved in cellular trafficking, including microtubule bundling and endocytosis. Mx1, also known as MxA, an interferon (IFN)-induced protein, acquires a high degree of resistance to influenza A virus and the rhabdo-virus vesicular stomatitis virus (VSV), which suggests that Mx1 plays an active role against influenza virus and the rhabdovirus VSV. Mx1 is a cytoplasmic protein that is 63% identical to the Mx2 protein, which lacks antiviral activity. Mx2 is also known as MxB and is localized at the cytoplasmic face of nuclear pores. Mx2 expression is not interferon-dependent and this protein is thought to regulate the efficiency and/or kinetics of nuclear import, a function which may have been usurped by its antiviral relatives.

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SPECIFICATIONS

Catalog Number

BS5805P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide MX2. (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P20592

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS5805 MX2 pAb.

Alternative Names

Interferon-induced GTP-binding protein Mx2; Interferon-regulated resistance GTP-binding; protein MxB; Myxovirus resistance protein 2; p78-related protein