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MYL12B, NT (MYL12B, MRLC2, MYLC2B, Myosin regulatory light chain 12B, MLC-2A, Myosin regulatory light chain 2-B, smooth muscle isoform, Myosin regulatory light chain 20kD, Myosin regulatory light chain MRLC2, SHUJUN-1) (APC)

Cat no: 038733-APC

MYL12B, NT (MYL12B, MRLC2, MYLC2B, Myosin regulatory light chain 12B, MLC-2A, Myosin regulatory light chain 2-B, smooth muscle isoform, Myosin regulatory light chain 20kD, Myosin regulatory light chain MRLC2, SHUJUN-1) (APC)

The activity of nonmuscle myosin II (see MYH9; MIM 160775) is regulated by phosphorylation of a regulatory light chain, such as MRLC2. This phosphorylation results in higher MgATPase activity and the assembly of myosin II filaments (Iwasaki et al., 2001 [PubMed 11942626]).\n\nApplications:\nSuitable for use in Western Blot, ELISA\n\nRecommended Dilution:\nELISA: 1:1,000\nWestern Blot: 1:100-500\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze APC conjugates. Light sensitive. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

038733-APC

Size

200ul

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to Allophycocyanin (APC).

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

References

Martins-de-Souza, D., et al. Eur Arch Psychiatry Clin Neurosci 259(3):151-163(2009)\nUmeda, D., et al. Biochem. Biophys. Res. Commun. 333(2):628-635(2005)\nLi, T.B., et al. Acta Biochim. Biophys. Sin. (Shanghai) 36(6):412-418(2004)\nWebb, R.C. Adv Physiol Educ 27 (1-4), 201-206 (2003) :\nIwasaki, T., et al. Cell Struct. Funct. 26(6):677-683(2001)

Additional Info

Human

Alternative Names

MYL12B, MRLC2, MYLC2B, Myosin regulatory light chain 12B, MLC-2A, Myosin regulatory light chain 2-B, smooth muscle isoform, Myosin regulatory light chain 20kD, Myosin regulatory light chain MRLC2, SHUJUN-1

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