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Nerve Growth Factor, pro (Pro-brain nerve growth factor, proNGF, NGF)

Cat no: N2350-09J

Nerve Growth Factor, pro (Pro-brain nerve growth factor, proNGF, NGF)

Nerve growth factor (NGF) is synthesized as a precursor (proNGF) which may be released and have physiological functions to cause cell death. It binds neurotrophin receptor p75 and sortilin and may also be important for the development of nervous system. proNGF is synthesized in target tissues and glia, transported retrogradely and may be released. This antibody is raised in sheep to detect the prodomain of NGF not the mature peptide.\n\nApplications: \nSuitable for use in Immunohistochemistry, Immnunofluorescence, ELISA, Western Blot and Neutralization. Other applications have not been tested. \n\nRecommended Dilutions: \nOptimal dilutions to be determined by the researcher. \n\nStorage and Stability:\nLyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

N2350-09J

Size

100ul

Applications

ELISA, IF, IHC, WB

Hosts

Sheep

Reactivities

Hum, Mouse, Rat

Form

Supplied as a lyophilized powder. Reconstitute with 100ul sterile ddH2O.

P Type

Pab

Purity

Serum

Isotype

IgG

Additional Info

Recognizes human proNGF. Does not crossreact with proBDNF, proNT-3 or mature NGF. Species crossreactivity: mouse and rat.

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