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Netrin-1, Recombinant, Human (NTN1)

Netrin-1, Recombinant, Human (NTN1)

Cat no: 045077

Supplier: United States Biological
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Netrin-1 controls guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Netrin-1 is also Involved in tumorigenesis by regulating apoptosis. Biological Activity: Induces axon outgrowth. Sequence: Human netrin-1 (aa 25-604) is fused at the N-terminus to a FLAG(R)-tag. Storage and Stability: Short-term Storage: +4 degrees C Long-term Storage: -20 degrees C Stable for at least 6 months after receipt when stored at -20 degrees C.
Catalogue number: 045077
Size: 10ug
Form: Supplied as a lyophilized powder from a 0.2um filtered solution in PBS pH 7.2, with trehalose and Brij35.
Purity: >95% (SDS-PAGE)
Alternative names: NTN1
Additional info: Binds to human, mouse and rat UNC5B.

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