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Neurexin 1b

Cat no: N2110-04

Neurexin 1b

Neurexin 1 beta is an 80kD member of the Neurexin family of proteins. It is expressed on neuronal presynaptic membranes and contributes to synapse formation through binding to postsynaptic neuroligins. An alternate start site in the Neurexin 1 gene generate an a- (long) and B- (short) isoform. Mature rat Neurexin 1B is a type I transmembrane glycoprotein that is 468 amino acids (aa) in length. It has a 346 aa extracellular region (aa 47-392) that contains one laminin-like G domain (aa 91-264). Within the G domain, the presence or absence of a splice site (aa 201-230) materially impacts neuroligin binding. Over aa 47-392, rat Neurexin 1B is 100% and 98% aa identical to mouse and human Neurexin 1B, respectively.\n\nApplications: \nSuitable for use in Direct ELISA and Western Blot. Other applications not tested.\n\nRecommended Dilution:\nDiretc ELISA: 0.5-1.0ug/ml detection limit for rrNeurexin 1Beta is ~ 0.5ng/well.\nWestern Blot: 1.0ug/ml\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nLyophilized powder may be stored at -20 degrees C. Reconstitute to nominal volume by adding sterile 40-50% glycerol, aliquot and store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

N2110-04

Size

100ug

Applications

ELISA, WB

Hosts

Sheep

Reactivities

Rat

Form

Supplied as a lyophilized powder in PBS, 5% trehalose. Reconstitute with 1000ul sterile 40-50% glycerol, PBS.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG

Additional Info

Recognizes rat Neurexin 1Beta.

Read more on Supplier website

Applications

ELISA

Reactivities

Hum

More info

Applications

IF

Hosts

Mouse

More info

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info
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