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Neurofibromin (NF1, WSS, NFNS, VRNF, NF, Neurofibromin  1, neurofibromatosis, type I, von  Recklinghausen disease neurofibromin,  Neurofibromatosis-Noonan syndrome, WATS,  Watson Syndrome)

Cat no: N2150-01D

Neurofibromin (NF1, WSS, NFNS, VRNF, NF, Neurofibromin 1, neurofibromatosis, type I, von Recklinghausen disease neurofibromin, Neurofibromatosis-Noonan syndrome, WATS, Watson Syndrome)

NF1 contains a GTPase-activating protein-related domain (GRD), and is involved in the negative regulation of Ras proteins, by accelerating the hydrolysis of active Ras-guanosine triphosphate.\nMutations of NF1 have been reported in Neurofibromatosis type 1, which is characterized by a predisposition to a variety of tumors of the peripheral and central nervous systems as well as myeloid leukemia, cognitive deficits, bone deformations, and pigmentation defects.\n\nApplications:\nSuitable for use in Western Blot and Immunoprecipitation. Other applications not tested. \n\nRecommended Dilution: \nWestern Blot: 1: 500-1: 5000\nImmunoprecipitation: 2-10ug/mg protein\nOptimal dilution determined by the researcher.\n\nRecommended Secondary Reagents: \nSheep anti rabbit IgG: HRP\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

N2150-01D

Size

50ug

Applications

IP, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in Tris-citrate/phosphate, 0.09% sodium azide before the addition of glycerol to 40%.

P Type

Pab

Purity

Purified by affinity chromatography.

Isotype

IgG

Additional Info

Specific for human Neurofibromin 1 (NF1), the protein product of the NF1 tumor suppressor gene.

Read more on Supplier website

Applications

ELISA

Reactivities

Hum

More info

Applications

IF

Hosts

Mouse

More info

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info
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