Newcastle Disease Virus (NDV)

The Newcastle Disease Virus (NDV) is a highly contagious avian virus which is of major economic importance to the poultry industry. NDV is a member of the Paramyxoviridae family, and has a single stranded, negative sense RNA genome. NDV infects via mucosal surfaces of the respiratory and alimentary tract, and its strains can be categorized in accordance to their virulence, from low virulence and mild symptoms (lentogenic), to intermediate forms (mesogenic), through to highly virulent (velogenic) strains which can cause up to 90% mortality. La-Sota is a lentogenic strain, and can be used as a live vaccine.\n\nApplications: \nSuitable for use in ELISA. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nHybridoma: \nSp2/0 myeloma cells with spleen cells from Balb/c mice.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

N2275-01A

Size

200ug

Applications

ELISA

Hosts

Mouse

Form

Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.

P Type

Mab

Purity

Purified by Protein G affinity chromatography.

Isotype

IgG1

References

1. Lorence, R.M. et al. (2007) Phase 1 clinical experience using intravenous administration of PV701, an oncolytic Newcastle disease virus. Curr. Cancer Drug Targets. 7: 157-67.2. Huang Z. et al. (2003) Recombinant Newcastle disease virus as a vaccine vector. Poult. Sci. 82: 899-906.

Additional Info

Recognizes the La-Sota strain of the Newcastle Disease Virus (NDV), a highly contagious avian virus which is of major economic importance to the poultry industry. NDV is a member of the Paramyxoviridae family, and has a single stranded, negative sense RNA genome.