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NF?B-p100 Polyclonal Antibody

Cat no: ABP51944

NF?B-p100 Polyclonal Antibody

NFKB2 encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. Nuclear factor kappa B subunit 2 encoded by NFKB2 can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for NFKB2 on chromosome 18. Alternative splicing results in multiple transcript variants.

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SPECIFICATIONS

Catalog Number

ABP51944

Size

30micro l, 100micro l, 200micro l

Applications

ELISA, IF, IHC-F, IP, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Gene Id

4791

Isotype

Rabbit IgG

Accession

Q00653

Clonality

Polyclonal

Concentration

1 mg/ml

SUPPLIER INFO

Abbkine Scientific Co.Ltd.

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