NF-H Antibody

Cat no: 250768

Supplier: ABBIOTEC

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Description
Additional Information

Neurofilament triplet H protein (NF-H) is one of the three intermediate filament proteins (L,Mouse, and H) making up neurofilaments. NF-H is involved in the maintenance of neuronal caliber. NF-H has an important function in mature a, Xenopus/Amphibian,ons that is not subserved by the two smaller NF proteins. Phosphorylation plays a major role in the functioning of the larger neurofilament polypeptides (NF-M and NF-H), the levels of phosphorylation being altered developmentally and coincident wih a change in the neurofilament function. Defects in NF-H are a cause of susceptibility to amyotrophic lateral sclerosis (ALS), a neurodegenerative disorder affecting upper and lower motor neurons resulting in fatal paralysis.

Catalogue number:	250768
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P12036
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the center region of human NF-H.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Neurofilament heavy polypeptide; NF-H; Neurofilament triplet H protein; 200 kDa neurofilament protein; NEFH; NFH