NFKB p50 Antibody

Cat no: 251563

Supplier: ABBIOTEC

0 reviews | Write a Review Pencil

Description
Additional Information

NF-kappa-B p50 subunit (NFKB p50) is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B comple, Xenopus/Amphibian,es are held in the cytoplasm in an inactive state comple, Xenopus/Amphibian,ed with members of the NF-kappa-B inhibitor (I-kappa-B) family. In a conventional activation pathway, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, is subsequently degraded thus liberating the active NF-kappa-B comple, Xenopus/Amphibian, which translocates to the nucleus. NF-kappa-B heterodimeric p65-p50 and RelB-p50 comple, Xenopus/Amphibian,es are transcriptional activators. The NF-kappa-B p50-p50 homodimer is a transcriptional repressor, but can act as a transcriptional activator when associated with BCL3.

Catalogue number:	251563
Reactivities:	Human, Mouse, Bovine, Chicken/Bird, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P19838
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within human NFKB p50.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Nuclear factor NF-kappa-B p105/p50 subunit; DNA-binding factor KBF1; EBP-1; NFKB1; Nuclear factor NF-kappa-B p50 subunit; NFKB p105/p50