NGF-beta Antibody

Cat no: 250773

Supplier: ABBIOTEC

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Description
Additional Information

Nerve growth factor (NGF) is important for the development , differentation, and survival of a variety of neuronal and non-neuronal cells. NGF action is mediated by binding to two distinct receptors, the high affinity p140 and low affinity p75 NGF receptors. P75NGFR binds neurotrophins including brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), neurotrophin 4/5 (NT-4/5) and NT-6. p75NGFR belongs to the TNF-R superfamily reported to mediate NGF-induced apoptosis. Defects in NGF are the cause of hereditary sensory and autonomic neuropathies.

Catalogue number:	250773
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P01138
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human NGF.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Beta-nerve growth factor; beta-NGF; NGF; NGFB