NHE-7 (D566) Peptide

Cat no: BS3400P

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

Na+/H+ exchangers (NHE) of mammalian cells are plasma membrane intrinsic proteins mediating exchange of N+ and H+ ions in various tissues. The NHE catalyzes the electroneural transport of extracellular Na+ for intracellular H+. They play a major role in regulation of intracellular pH (pHi) in addition to trans-cellular absorption of Na+, cell volume regulation and possibly in cell proliferation. These primary functions of the Na+/H+ exchanger have been related to many pathophysiological states, include hypertension, organ growth and hypertrophy, regression of cancer and renal intestinal disorders. At least 7 NHE isoforms (NHE1-7) have been cloned so far. They are all similar in their primary structure and predicted to have 10-12 transmembrane domains. The C-terminal domain of NHEs are predicted to be intracellular. NHE7 (human 725 aa, chromosome Xp11.4) is ubiquitously expressed, and predominantly localizes to the trans-golgi network. NHE7 mediates the influx of Na+ or K+ in exchange for H+. It is ~70% related to NHE6 but relatively less (~25%) homologous with other NHEs.

Catalogue number:	BS3400P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	Q96T83
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide NHE-7 (D566). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	SLC9A7; NA; NHE-7; NHE7; SLC9A6
Additional info:	This peptide can be used with studies using BS3400 NHE-7 (D566) pAb.

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NHE-7 (D566) Peptide

Cat no: BS3400P

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