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NK1.1 (CD161, CLEC5B, KLRB1, KLRB-1C, Klrb1c, Ly59, NKR, NKRP1, NKRP1A)

Cat no: 145551

NK1.1 (CD161, CLEC5B, KLRB1, KLRB-1C, Klrb1c, Ly59, NKR, NKRP1, NKRP1A)

KLRB1C, also known as NK1.1, CD161c, Ly-55, and NKR-P1c, is a 28kD type 2 transmembrane protein in the killer cell lectin-like receptor family. CD161 is expressed as a disulfide-linked homodimer on the surface of NK cells and subpopulations of NKT, CD4+, CD8+, and gamma/delta T cells. Its cross-linking on NK cells induces cytolytic activity, and on CD4 cells it promotes IgE production and the expansion of Th2 responses. Mature mouse CD161 consists of a 45 amino acid (aa) cytoplasmic domain, a 21aa transmembrane segment, and a 157aa extracellular domain with one C-type lectin domain.\n\nApplications: \nSuitable for use in Flow Cytometry. Other applications not tested.\n\nRecommended Dilution:\nFlow Cytometry: 2.5ug/10e6cells\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nLyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

145551

Size

100ug

Applications

FC

Hosts

Rat

Reactivities

Mouse

Form

Supplied as a lyophilized powder in PBS, Trehalose. Reconstitute in sterile PBS.

P Type

Mab

Purity

Purified by Protein A or G affinity chromatography.

Isotype

IgG2a

Additional Info

Recognizes mouse CD161/KLRB

Read more on Supplier website

Applications

ELISA, IHC, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

More info

Applications

ELISA, IHC, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

More info

Applications

ELISA, IHC, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

More info
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