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NKp30 (L134) pAb

NKp30 (L134) pAb

Cat no: BS3888

Supplier: Bioworld Technology, Inc.
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The p30-15 monoclonal antibody recognizes CD337 also known as activating NK receptor NKp30 (NKp30), and natural cytotoxicity triggering receptor 3. NKp30 is a type I transmembrane protein, member of the natural cytotoxicity receptor family that contains one immunoglobulin-like domain. NKp30 has an apparent molecular weight of 30 kD and six isoforms are produced by alternative splicing. NKp30 is expressed on IL-2 activated NK cells and NK cell lines as well as some in vitro activated (gamma)/(delta) T cells. NKp30 enhances NK cell triggering and cytolysis of tumor targets and other target cells deficient in MHC class I molecules. NKp30 has been shown to associate with CD59 and TCR?. The p30-15 antibody against human NKp30 has been shown to be useful for flow cytometry, stimulation of human NK cells via NKp30 in a redirected lysis assay, and blocking of NKp30 function in solution.
Catalogue number: BS3888
Reactivities: Human, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: O14931
Dilutions: WB: 1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 111-160 of Human NKp30.
Species: NKp30 (L134) pAb detects endogenous levels of NKp30 protein.
Molecular weight: ~ 30 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: NKp30; NCR3; 1C7; LY117; CD337; NKp30; NK-p30; Natural cytotoxicity triggering receptor 3
Additional info: For research use only, not for use in diagnostic procedure.

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